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Tuesday, March 20, 2018

Russian chemists have provided a highly efficient method for early diagnosis of cancer

A new type of nanoparticles that allow, without harm to the body to detect even small and subtle cancers presented by Russian specialists from Kazan and Novosibirsk. Reportedly, the Russians developed the system allows you to “paint” the foci.

photo: pixabay.com

Experts underline that cancerous tumors usually differ from the healthy tissues of the body by their density, biological activity, temperature and other parameters, and therefore to detect them should be possible at the earliest stages. In particular, doctors may detect traces of it on special molecules that cancer cells secrete into the blood of a person, or make use of magnetic resonance imaging.

Today, many professionals develop a so-called contrast agents — substances that penetrate into cancerous tumors, accumulate there and “illuminate” her during a diagnostic session. One way to “backlight” and was proposed by Russian researchers

Scientists from Kazan and Novosibirsk examined nanoparticles of metal gadolinium, whose compounds are now widely used in the diagnosis of cancer using MRI. Pure gadolinium is quite toxic, but experts have proposed a method, which should help to avoid the negative impact of the substance on the body, reducing its effectiveness. For this proposed “package” ions of this metal in a chemically inert and harmless to human body, nanoparticles can penetrate and accumulate inside tumors.

According to the Kazan chemists, they developed particles have a record contrasting effect in excess of strength of the best modern gadolinium products are about 15-20 times, and they are much more stable, which can reduce the dose of contrast agent for diagnostics about 20 times, thus protecting the patient.

Issledovateli note that to date there are only a few analogues of nanoparticles. In the future safety developments will be tested in clinical trials.

The study was published in New Journal of Chemistry.


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