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Tuesday, March 13, 2018

In Russia, invented an artificial skin: thanks to the keratinocytes

Poor animals will soon cease to be subjects for testing cosmetic products in Russia. Novosibirsk scientists have developed a method of creating an artificial human skin on the basis of these cells are keratinocytes. As reported by “MK” at the Institute of biomedical chemistry of them. V. N. Orehovica, in the end it should be a test system designed to assess the safety of chemical products for health without the involvement of such experiments of living beings.

photo: pixabay.com

The developed test system is a cell model of normal human epidermis grown in a special cell boxes under sterile conditions with the addition of various substances. Initially it is a cell line grown from human keratinocytes. Analogues of artificial leather has long been bred abroad, but the Russian developers of cosmetic products, cannot use them. Samples tend to lose their properties after 1-2 days of cultivation, and carry the skin in our country, sometimes for weeks. Therefore, our scientists decided to create artificial human skin to experiment on in Russia.

After a dive in the box to the source material accumulates layers of the epidermis, like natural leather, after which it is difficult to distinguish from the real. The main goal of scientists is to create a new skin resistance to penetration of a number of chemical compounds. In addition to safe testing of cosmetic products such skin can be useful for preclinical studies of the safety of medicinal products intended for external use, and environmental monitoring.


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