Children who at birth weigh too much or too little in the future thicket vulnerable to type 2 diabetes and various diseases of the cardiovascular system. This is evidenced by the results of a larger study conducted by experts from the UK and the Netherlands. Also, experts were able to better understand the reasons why some children are born larger, in others smaller.
Scientists have summarized the results of 37 studies carried out previously, which together have involved more than 150 thousand people. As a result, the experts came to the conclusion that genetic differences between children constitute one of the key determinants of their weight at birth. The influence of genes was several times more important than such “external” background, as the weight of the mother or her penchant for Smoking. Even small genetic variations sometimes had a significant impact on the major if the baby is born.
Experts have discovered about 60 sites of the genome, influencing the baby’s weight at birth, and further investigation revealed that many of these sites affect a person’s predisposition to type 2 diabetes and diseases of the cardiovascular system in adulthood.
That is too high or too low weight of a newborn baby can be to be a sign of possible health problems in the future, has been known for a long time, scientists recognize. However, for a long time it was assumed that this relationship exists in the first place is not at the genetic level, but reflects certain features of the development of the embryo, due to other factors.
Experts hope that these data will allow the early stages to keep track of the predisposition of individuals to certain diseases, and to develop more effective methods to combat these diseases. Their work, the researchers published in the journal Nature.