A study conducted by the American experts from the University of Wake Fores in North Carolina, showed that from the point of view of biochemistry of alcohol affects the person as well as fast-acting antidepressants. According to experts, it is in any case no reason to equate alcohol to medications, however, allows you better understand why depressed people sometimes try to find getting rid of it on the bottom of the bottle.
In the experiment, the scientists injected laboratory animals dose of alcohol, sufficient to block the NMDA receptor, which was previously shown to be involved in working memory and the maintenance of learning ability. After this, the researchers monitored the changes occurring in their body and behavior of animals.
As it turned out, the alcohol not only block NMDA receptors, but also interacted with the protein FMRP (last was discovered his connection with disorders of the autistic spectrum), and turning them into gamma-aminobutyric acid from the compound, overwhelming the nervous activity, in substance it stimulating. This led to the fact that on the day the animals were rid of their symptoms of depression.
Experts note that processes such as those described above, occur in the body and under the influence of fast-acting antidepressants. At the same time, the behavior of animals under the influence of alcohol was varied in much the same way as the behavior of people.
According to the head of research Kimberly Raab-Graham, the results obtained from a biochemical point of view, to explain why people suffering from major depressive disorder often are also alcoholics. Apparently, people with clinical depression who feel “healing” effect of alcohol, begin to use them in the quest to beat depression, but instead to achieve this effect, and also be susceptible to alcohol addiction.
A new study published in the latest issue of the journal Nature Communications.