An international group of researchers from the UK, Germany and the United States attempted to better understand the nature of the sometimes observed relationship between diseases of the human immune system and predisposition to mental disorders like bipolar affective disorder (manic depression). As it turned out, sometimes these two problems represent elements of one chain and are based on genetic factors.
The experts summarized the results of several previous studies that tracked the relationship between people’s genes and phenotype – a set of characteristics inherent in the individual at a certain stage of development and evolving based on genotype, but is influenced by external factors. Specialists primarily interested in the DNA, one or the other “configuration” which, according to observations, could be simultaneously correlated with an increased risk of disorders in the immune system and serious mental disorders.
As a result, researchers, according to them, actually managed to find certain patterns, with high probability implying the relationship between serious psychological problems and diseases related to the functioning of the immune system. According to scientists, different genetic factors can lead to the disruption of the protective systems of the body, and this, in turn, can be fraught with mental problems. The relationship of this kind, according to experts, can sometimes be observed between bipolar disorder and these disorders, including autoimmune processes, such as celiac disease or ulcerative colitis.
Until that research is not published in any peer-reviewed journal, but an article on the results, the experts placed in the archive of preprints biorxiv.org.