A team of specialists representing the Massachusetts Institute of technology introduced a new technology to create so-called DNA origami objects of the nanometer size of chains of nucleic acids. According to scientists, they managed to develop an algorithm that automates this process and opens new opportunities for him, including in the area of the creation of nanorobots.
Experts note that the technology of DNA origami was previously known, however, for a long time, the establishment with it of any structures would be very difficult and “piece” work, so their application was considered to be very limited, and the number of specialists using this technology, was quite narrow. However, according to the developers, who published their study in the journal Science, they managed to create a new technique that will significantly simplify the Assembly procedure.
Unlike the traditional approach, the new method implies building a particular structure from scratch, and the creation of nucleic acids of simple geometric forms, which, in turn, could organize into something more complex, being placed in a special solution. Short DNA fragments, take many forms, and thus be “associated” with one of the longer fragment. In order to get this design together, will apply the principle of complementarity: the interaction of chains of nucleic acids nitrogenous bases of the nucleotides due to the formation of hydrogen bonds will form paired complexes of adenine—thymine and guanine—Chitose.
The new method, as scientists believe, allows to significantly simplify the process of creating DNA origami, but allows to “output” at least, and probably more complicated forms than those that were able to previously. According to the creators of the development, in the future it can be used not only in the creation of nanorobots, but also in geniticheskie engineering, the development of vaccines and for the production of ultra-compact storage media.Related posts: