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Tuesday, October 17, 2017

Genetically modified larvae will heal wounds


Previously, doctors used maggots Padalino green flies as a healing tool. Maggots eat dead tissue and leave living, moreover, they were isolated an antimicrobial substance, which kept the wound clean. In General, the method was cheap and effective but not quick. Clinical trials have shown that the use of larvae does not accelerate the healing of wounds, but new genetically modified creation can change everything, at least so says a new article published in the journal BMC Microbiology.

Human platelet derived growth factor is a signaling molecule that causes cells to divide rapidly. Also, experiments have shown that it helps wounds overgrown. The researchers have used insects for the production of growth factor, but never has this technique not used on the larvae of flies. Biologists from North Carolina made two “batches” of larvae. One was modified to produce factor when heated to 37 degrees Celsius. The other had made the necessary substance that if adhered to a diet that does not include the antibiotic tetracycline.

Heated larvae really started to produce the growth factor but from their bodies so it is not allocated, but purified from the tetracycline group of larvae were abundantly allocated the required substance in the secretions of the body and the waste products. Although larvae has not yet been tested in human wounds, researchers believe that these insects will become how to clean wounds and treat them, greatly reducing the time required for overgrowth of flesh.

This tool will especially help people with diabetes whose feet have a non-healing ulcer. And let the thought of worms who Tinkers in open wounds, unpleasant, but if they are to halve the healing time, the tool will be popular.

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